/ Side by side
Sermorelin vs Ipamorelin
A neutral, side-by-side look at Sermorelin and Ipamorelin: what each one is, its class, half-life, storage, and the public sources behind it. Educational reference only, not medical advice, dosing, or a recommendation to use either compound.
Sermorelin
Geref · GHRH 1-29
Full profile →Ipamorelin
Full profile →| Attribute | Sermorelin | Ipamorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Half-life | ~10-20 min | ~2 h, subcutaneous |
| Common vial | 5, 10 mg | 5, 10 mg |
| Reference | Verified | Verified |
What is Sermorelin?
A synthetic peptide corresponding to the first 29 amino acids of growth-hormone-releasing hormone that binds pituitary GHRH receptors to stimulate endogenous growth hormone secretion. Previously marketed (Geref) and used in diagnostic testing.
Sources
- FDA history: Geref
- DrugBank DB00010
What is Ipamorelin?
A selective ghrelin/growth-hormone-secretagogue receptor (GHS-R1a) agonist pentapeptide that stimulates pituitary growth hormone release with minimal effect on cortisol or prolactin.
Sources
- Raun et al., Eur J Endocrinol 1998
- Ishida et al. 2020 (GHS review)
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.