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Cognitive / LongevityVerified

5-Amino-1MQ

5A1MQ

A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied in preclinical metabolic research; by inhibiting NNMT it is reported to raise intracellular NAD+ and shift adipocyte metabolism toward oxidation. Not a peptide.

5-Amino-1MQ
Category
Cognitive / Longevity
Half-life
~3.8 h IV and ~6.9 h oral in rat; no published human PK
Common vial
50 mg
Regulatory
Research only

Tracking and educational reference only, on values you enter or import yourself. Not medical advice or a dosing recommendation.

01

Regulatory status

Research only

This substance is sold and handled as a research material and is not approved for human use. There is no approved label, which means there is no agency-reviewed information about how it should be handled, who should avoid it, or what happens alongside other medicines.

Not approved for human use

A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.

02

Half-life

~3.8 h IV and ~6.9 h oral in rat; no published human PK. Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.

03

Storage & handling

Small-molecule solid; store cool and dry, protected from light and moisture, in a sealed container.

04

References

  • Rat LC-MS/MS PK study
  • Neelakantan et al. (NNMT inhibitor, DIO models)

Read the source

Common questions

5-Amino-1MQ, answered plainly.

01What is 5-Amino-1MQ?+

A small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied in preclinical metabolic research; by inhibiting NNMT it is reported to raise intracellular NAD+ and shift adipocyte metabolism toward oxidation. Not a peptide. It is also referred to as 5A1MQ. It is listed here under Cognitive / Longevity as educational reference, which is not a recommendation to use it.

02Is 5-Amino-1MQ FDA approved?+

Research only. This substance is sold and handled as a research material and is not approved for human use. There is no approved label, which means there is no agency-reviewed information about how it should be handled, who should avoid it, or what happens alongside other medicines.

03What is the half-life of 5-Amino-1MQ?+

~3.8 h IV and ~6.9 h oral in rat; no published human PK. A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.

04How is 5-Amino-1MQ stored and handled?+

Small-molecule solid; store cool and dry, protected from light and moisture, in a sealed container. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.

05What vial strengths of 5-Amino-1MQ are commonly sold?+

Commonly listed vial strengths are 50 mg. A vial strength is a market fact about how a product is packaged. It is not a dose, and it says nothing about how much of anything belongs in any person.

Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.