Exenatide
Byetta · Bydureon
The first GLP-1 receptor agonist brought to market, a synthetic version of exendin-4. Its short terminal half-life is why the original formulation is twice-daily, in contrast to the weekly agonists that followed.
Tracking and educational reference only, on values you enter yourself. Not medical advice or a dosing recommendation.
Regulatory status
FDA approved
The FDA has approved at least one product containing this substance for a specific medical use, which means it has been through the agency review process and carries an approved label. Approval is always for named indications in named populations, so it is not a statement that any other use has been evaluated.
A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.
Half-life
~2.4 h (terminal), subcutaneous. Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.
Storage & handling
Supplied as a refrigerated prefilled pen; protect from light and do not freeze.
What the label says about other medicines
The approved label for Exenatide carries 3 transcribed notes, each restating a numbered section rather than offering advice of our own.
References
- FDA label: Byetta (NDA 021773)
Read the source
Common questions
Exenatide, answered plainly.
01What is Exenatide?+
The first GLP-1 receptor agonist brought to market, a synthetic version of exendin-4. Its short terminal half-life is why the original formulation is twice-daily, in contrast to the weekly agonists that followed. It is also referred to as Byetta, Bydureon. It is listed here under GLP-1 / Metabolic as educational reference, which is not a recommendation to use it.
02Is Exenatide FDA approved?+
FDA approved. The FDA has approved at least one product containing this substance for a specific medical use, which means it has been through the agency review process and carries an approved label. Approval is always for named indications in named populations, so it is not a statement that any other use has been evaluated.
03What is the half-life of Exenatide?+
~2.4 h (terminal), subcutaneous. A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.
04How is Exenatide stored and handled?+
Supplied as a refrigerated prefilled pen; protect from light and do not freeze. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.
05What does the Exenatide label say about other medicines?+
The approved label carries 3 transcribed notes covering other oral medications, insulin and insulin secretagogues, warfarin. Each one restates a numbered section of the label rather than offering advice of our own. Absence of a topic means nothing was transcribed, not that a combination is safe.
Compare Exenatide
Related in GLP-1 / Metabolic
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.