GIP
Glucose-dependent insulinotropic polypeptide · Gastric inhibitory polypeptide
One of the two main incretin hormones, released from the gut after eating and acting at the GIP receptor. It is the second target that dual agonists such as tirzepatide combine with GLP-1, which is why it appears in discussion of that class. An endogenous hormone, not a marketed product on its own.
Tracking and educational reference only, on values you enter or import yourself. Not medical advice or a dosing recommendation.
Regulatory status
Not FDA approved
The FDA has not approved this substance for human use. It may be approved elsewhere, studied in the literature, or available through other routes, but it carries no approved US label and therefore no agency-reviewed instructions.
A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.
Half-life
Minutes in circulation, being rapidly inactivated by DPP-4. Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.
Storage & handling
No approved label defines handling.
References
- Molecular Metabolism 2025: glucose-dependent insulinotropic polypeptide (GIP), a review
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Common questions
GIP, answered plainly.
01What is GIP?+
One of the two main incretin hormones, released from the gut after eating and acting at the GIP receptor. It is the second target that dual agonists such as tirzepatide combine with GLP-1, which is why it appears in discussion of that class. An endogenous hormone, not a marketed product on its own. It is also referred to as Glucose-dependent insulinotropic polypeptide, Gastric inhibitory polypeptide. It is listed here under GLP-1 / Metabolic as educational reference, which is not a recommendation to use it.
02Is GIP FDA approved?+
Not FDA approved. The FDA has not approved this substance for human use. It may be approved elsewhere, studied in the literature, or available through other routes, but it carries no approved US label and therefore no agency-reviewed instructions.
03What is the half-life of GIP?+
Minutes in circulation, being rapidly inactivated by DPP-4. A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.
04How is GIP stored and handled?+
No approved label defines handling. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.
Related in GLP-1 / Metabolic
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.