ACE-031
ActRIIB-Fc · Ramatercept
A soluble form of the activin receptor type IIB fused to an antibody Fc region, designed to bind myostatin and related ligands before they reach the receptor. Studied in early clinical trials that were later discontinued. Not approved.
Tracking and educational reference only, on values you enter or import yourself. Not medical advice or a dosing recommendation.
Regulatory status
Investigational
This substance is under study in humans, typically under a regulatory authorization such as an Investigational New Drug application. Investigational describes a stage of research and nothing more: it does not mean approval is coming, and it does not indicate that effectiveness has been established.
A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.
Half-life
Not established in a public source. Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.
Storage & handling
Investigational; no approved label defines handling.
References
- PLoS One 2026: ACE-031, a soluble activin type IIB receptor, in a non-human primate model
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Common questions
ACE-031, answered plainly.
01What is ACE-031?+
A soluble form of the activin receptor type IIB fused to an antibody Fc region, designed to bind myostatin and related ligands before they reach the receptor. Studied in early clinical trials that were later discontinued. Not approved. It is also referred to as ActRIIB-Fc, Ramatercept. It is listed here under Growth Hormone as educational reference, which is not a recommendation to use it.
02Is ACE-031 FDA approved?+
Investigational. This substance is under study in humans, typically under a regulatory authorization such as an Investigational New Drug application. Investigational describes a stage of research and nothing more: it does not mean approval is coming, and it does not indicate that effectiveness has been established.
03What is the half-life of ACE-031?+
Not established in a public source. A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.
04How is ACE-031 stored and handled?+
Investigational; no approved label defines handling. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.
Related in Growth Hormone
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.