Macimorelin
Macrilen · AEZS-130
An orally administered ghrelin receptor agonist approved as a diagnostic agent. It stimulates growth hormone release so the response can be measured when adult growth hormone deficiency is being assessed. It is a diagnostic test, not a treatment.
Tracking and educational reference only, on values you enter or import yourself. Not medical advice or a dosing recommendation.
Regulatory status
FDA approved
The FDA has approved at least one product containing this substance for a specific medical use, which means it has been through the agency review process and carries an approved label. Approval is always for named indications in named populations, so it is not a statement that any other use has been evaluated.
A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.
Half-life
~4.1 h terminal, oral. Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.
Storage & handling
Supplied as granules in a pouch, reconstituted in water before use per its label.
References
- FDA label: Macrilen (NDA 205598)
- Expert Rev Mol Diagn 2014: the macimorelin-stimulated growth hormone test
- touchREV Endocrinol 2022: macimorelin acetate in childhood-onset growth hormone deficiency
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Common questions
Macimorelin, answered plainly.
01What is Macimorelin?+
An orally administered ghrelin receptor agonist approved as a diagnostic agent. It stimulates growth hormone release so the response can be measured when adult growth hormone deficiency is being assessed. It is a diagnostic test, not a treatment. It is also referred to as Macrilen, AEZS-130. It is listed here under Growth Hormone as educational reference, which is not a recommendation to use it.
02Is Macimorelin FDA approved?+
FDA approved. The FDA has approved at least one product containing this substance for a specific medical use, which means it has been through the agency review process and carries an approved label. Approval is always for named indications in named populations, so it is not a statement that any other use has been evaluated.
03What is the half-life of Macimorelin?+
~4.1 h terminal, oral. A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.
04How is Macimorelin stored and handled?+
Supplied as granules in a pouch, reconstituted in water before use per its label. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.
05What vial strengths of Macimorelin are commonly sold?+
Commonly listed vial strengths are 60 mg. A vial strength is a market fact about how a product is packaged. It is not a dose, and it says nothing about how much of anything belongs in any person.
Related in Growth Hormone
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.