MOTS-c
MOTSc
A 16-amino-acid mitochondrial-derived peptide (encoded within mitochondrial 12S rRNA) that activates AMPK and influences metabolic and mitochondrial pathways, studied as an exercise-mimetic and for metabolic homeostasis.
Tracking and educational reference only, on values you enter or import yourself. Not medical advice or a dosing recommendation.
Regulatory status
Research only
This substance is sold and handled as a research material and is not approved for human use. There is no approved label, which means there is no agency-reviewed information about how it should be handled, who should avoid it, or what happens alongside other medicines.
Not approved for human use
A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.
Half-life
Not well characterized in humans; preclinical estimates short (~45 min to a few hours). Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.
Storage & handling
Supplied lyophilized; store cool, reconstitute before use, then refrigerate and protect from light.
References
- Lee et al., Cell Metab 2015
- Reynolds et al. 2021
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Common questions
MOTS-c, answered plainly.
01What is MOTS-c?+
A 16-amino-acid mitochondrial-derived peptide (encoded within mitochondrial 12S rRNA) that activates AMPK and influences metabolic and mitochondrial pathways, studied as an exercise-mimetic and for metabolic homeostasis. It is also referred to as MOTSc. It is listed here under GLP-1 / Metabolic as educational reference, which is not a recommendation to use it.
02Is MOTS-c FDA approved?+
Research only. This substance is sold and handled as a research material and is not approved for human use. There is no approved label, which means there is no agency-reviewed information about how it should be handled, who should avoid it, or what happens alongside other medicines.
03What is the half-life of MOTS-c?+
Not well characterized in humans; preclinical estimates short (~45 min to a few hours). A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.
04How is MOTS-c stored and handled?+
Supplied lyophilized; store cool, reconstitute before use, then refrigerate and protect from light. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.
05What vial strengths of MOTS-c are commonly sold?+
Commonly listed vial strengths are 5, 10 mg. A vial strength is a market fact about how a product is packaged. It is not a dose, and it says nothing about how much of anything belongs in any person.
Compare MOTS-c
Related in GLP-1 / Metabolic
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.