Pentosan Polysulfate
PPS · Elmiron
A semi-synthetic sulfated polysaccharide (heparin-like glycosaminoglycan), FDA-approved (Elmiron) for the pain of interstitial cystitis; thought to replenish the protective glycosaminoglycan layer of the bladder wall, with anti-inflammatory properties.
Tracking and educational reference only, on values you enter or import yourself. Not medical advice or a dosing recommendation.
Regulatory status
FDA approved
The FDA has approved at least one product containing this substance for a specific medical use, which means it has been through the agency review process and carries an approved label. Approval is always for named indications in named populations, so it is not a statement that any other use has been evaluated.
A regulatory status describes paperwork, not safety. An approved compound can still be wrong for a given person, and an unapproved one is neither thereby dangerous nor thereby fine.
Half-life
~20-27 h (plasma radioactivity), oral. Half-life is an educational pharmacology figure, drawn from public sources, and is not a schedule or dosing instruction.
Storage & handling
Marketed as 100 mg oral capsules (Elmiron); store at controlled room temperature per label.
References
- FDA label: Elmiron (1996)
Common questions
Pentosan Polysulfate, answered plainly.
01What is Pentosan Polysulfate?+
A semi-synthetic sulfated polysaccharide (heparin-like glycosaminoglycan), FDA-approved (Elmiron) for the pain of interstitial cystitis; thought to replenish the protective glycosaminoglycan layer of the bladder wall, with anti-inflammatory properties. It is also referred to as PPS, Elmiron. It is listed here under Healing / Recovery as educational reference, which is not a recommendation to use it.
02Is Pentosan Polysulfate FDA approved?+
FDA approved. The FDA has approved at least one product containing this substance for a specific medical use, which means it has been through the agency review process and carries an approved label. Approval is always for named indications in named populations, so it is not a statement that any other use has been evaluated.
03What is the half-life of Pentosan Polysulfate?+
~20-27 h (plasma radioactivity), oral. A half-life is an educational pharmacology figure describing how long the body takes to clear half of a substance. It is not a schedule and does not imply one.
04How is Pentosan Polysulfate stored and handled?+
Marketed as 100 mg oral capsules (Elmiron); store at controlled room temperature per label. Storage conditions come from a manufacturer's own label where one exists, and a compound with no approved label has no agency-reviewed handling instructions at all.
Related in Healing / Recovery
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.