Sexual & Hormonal Peptides
Sexual and hormonal compounds include melanocortin receptor agonists and peptides that act on the hypothalamic-pituitary-gonadal axis, studied in reproductive and sexual-health research. The group spans FDA-approved products and research-only materials, so handling and regulatory status vary widely from entry to entry.
7 compounds
PT-141
Bremelanotide · Vyleesi
A synthetic melanocortin receptor agonist that acts on central pathways involved in sexual arousal. FDA-approved as Vyleesi and studied for hypoactive sexual desire disorder in premenopausal women.
Melanotan II
MT-2 · MT2
A synthetic cyclic analog of alpha-melanocyte-stimulating hormone acting as a non-selective melanocortin receptor agonist. Studied in relation to skin pigmentation and, via MC4R activation, sexual arousal. Not FDA-approved.
Kisspeptin
Kisspeptin-10 · Kisspeptin-54
Endogenous neuropeptides (KISS1 products) that agonize the KISS1R/GPR54 receptor on hypothalamic GnRH neurons, stimulating pulsatile GnRH release and downstream LH and FSH secretion. Studied in reproductive neuroendocrinology and fertility research.
Gonadorelin
GnRH · Factrel
A synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH) that binds pituitary GnRH receptors to stimulate release of LH and FSH. Pulsatile use stimulates them; continuous use suppresses them.
HCG
Human Chorionic Gonadotropin · Novarel
A glycoprotein hormone that acts as a functional analog of luteinizing hormone, binding LH/CG receptors to stimulate gonadal steroidogenesis. FDA-approved for uses including ovulation induction and certain hypogonadotropic conditions. Dosed in international units.
Oxytocin
Pitocin
An endogenous nonapeptide hormone. Its approved label covers obstetric use rather than the social or behavioural effects it is often discussed for, and it is cleared from plasma within minutes.
Afamelanotide
Scenesse · Melanotan-1 · Melanotan I
A melanocortin-1 receptor agonist approved to increase pain-free light exposure in adults with erythropoietic protoporphyria, a rare photosensitivity disorder. It is delivered as a controlled-release implant. Its approved use is photoprotection, not weight, performance or sexual function.
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Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.